Pictures are always helpful with troubleshooting painting questions. Since you feel it's fish-eyes and someone has recommended to apply a medium first coat, you're probably asking yourself how to achieve that.
First, what type of spray gun do you have?......how many turns out from closed for the fluid adjustment, and how many turns out on the fan adjustment?......
Next will be how far away from the panel are you spraying, and how fast or slow are you moving the gun?
How your spraygun is set up and how fast or slow you move while spraying is critical in obtaining a good smooth, flat coverage of paint.
Example...... setting up a spraygun with a narrow fan pattern, lots of fluid volume, and slow moving spray pattern will pile on the paint causing many issues, such as, crating and runs. I associate fish-eyes with contamination, such as water or oil in the air supply.
So tell us about your gun set up and air supply? Remember, pictures are helpful.